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Brca1 is expressed in human microglia and is dysregulated in human and animal model of ALS
BACKGROUND: There is growing evidence that microglia are key players in the pathological process of amyotrophic lateral sclerosis (ALS). It is suggested that microglia have a dual role in motoneurone degeneration through the release of both neuroprotective and neurotoxic factors. RESULTS: To identif...
Autores principales: | Noristani, Harun Najib, Sabourin, Jean Charles, Gerber, Yannick Nicolas, Teigell, Marisa, Sommacal, Andreas, dM Vivanco, Maria, Weber, Markus, Perrin, Florence Evelyne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521418/ https://www.ncbi.nlm.nih.gov/pubmed/26227626 http://dx.doi.org/10.1186/s13024-015-0023-x |
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