Invader probes: harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications

Development of probes capable of recognizing specific regions of chromosomal DNA has been a long-standing goal for chemical biologists. Current strategies such as PNA, triplex-forming oligonucleotides, and polyamides are subject to target choice limitations and/or necessitate non-physiological condi...

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Detalles Bibliográficos
Autores principales: Guenther, Dale C., Anderson, Grace H., Karmakar, Saswata, Anderson, Brooke A., Didion, Bradley A., Guo, Wei, Verstegen, John P., Hrdlicka, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521421/
https://www.ncbi.nlm.nih.gov/pubmed/26240741
http://dx.doi.org/10.1039/c5sc01238d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521421/
https://www.ncbi.nlm.nih.gov/pubmed/26240741
http://dx.doi.org/10.1039/c5sc01238d

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