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Invader probes: harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications
Development of probes capable of recognizing specific regions of chromosomal DNA has been a long-standing goal for chemical biologists. Current strategies such as PNA, triplex-forming oligonucleotides, and polyamides are subject to target choice limitations and/or necessitate non-physiological condi...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521421/ https://www.ncbi.nlm.nih.gov/pubmed/26240741 http://dx.doi.org/10.1039/c5sc01238d |