Measuring windows of selection for anti-malarial drug treatments

BACKGROUND: The long half-lives of malaria ‘partner’ drugs are a potent force selecting for drug resistance. Clinical trials can quantify this effect by estimating a window of selection (WoS), defined as the amount of time post-treatment when drug levels are sufficiently high that resistant parasite...

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Detalles Bibliográficos
Autores principales: Kay, Katherine, Hastings, Ian M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521485/
https://www.ncbi.nlm.nih.gov/pubmed/26228915
http://dx.doi.org/10.1186/s12936-015-0810-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521485/
https://www.ncbi.nlm.nih.gov/pubmed/26228915
http://dx.doi.org/10.1186/s12936-015-0810-4

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