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Measuring windows of selection for anti-malarial drug treatments
BACKGROUND: The long half-lives of malaria ‘partner’ drugs are a potent force selecting for drug resistance. Clinical trials can quantify this effect by estimating a window of selection (WoS), defined as the amount of time post-treatment when drug levels are sufficiently high that resistant parasite...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521485/ https://www.ncbi.nlm.nih.gov/pubmed/26228915 http://dx.doi.org/10.1186/s12936-015-0810-4 |