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p27(Kip1) and Ser10-phosphorylated p27(Kip1) in breast cancer: clinical significance and expression
BACKGROUND: The protein p27 (p27(Kip1)) is a member of the cyclin-dependent kinase inhibitor family, which negatively regulates cell cycle progression, and the phosphorylation of p27 has been proven to affect its stability and nuclear export. Clinical studies on the relation between p27 and phosphor...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521679/ https://www.ncbi.nlm.nih.gov/pubmed/26244023 http://dx.doi.org/10.2147/OTT.S85866 |