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The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres
Dyskeratosis Congenita (DC) is a heritable multi-system disorder caused by abnormally short telomeres. Clinically diagnosed by the mucocutaneous symptoms, DC patients are at high risk for bone marrow failure, pulmonary fibrosis, and multiple types of cancers. We have recapitulated the most common DC...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521702/ https://www.ncbi.nlm.nih.gov/pubmed/26230315 http://dx.doi.org/10.1371/journal.pgen.1005410 |