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A Genetic Incompatibility Accelerates Adaptation in Yeast

During mismatch repair (MMR) MSH proteins bind to mismatches that form as the result of DNA replication errors and recruit MLH factors such as Mlh1-Pms1 to initiate excision and repair steps. Previously, we identified a negative epistatic interaction involving naturally occurring polymorphisms in th...

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Detalles Bibliográficos
Autores principales: Bui, Duyen T., Dine, Elliot, Anderson, James B., Aquadro, Charles F., Alani, Eric E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521705/
https://www.ncbi.nlm.nih.gov/pubmed/26230253
http://dx.doi.org/10.1371/journal.pgen.1005407