The Adaptive Change of HLA-DRB1 Allele Frequencies Caused by Natural Selection in a Mongolian Population That Migrated to the South of China

Pathogen-driven balancing selection determines the richness of human leukocyte antigen (HLA) alleles. Changes in the pathogen spectrum may cause corresponding changes in HLA loci. Approximately 700 years ago, a Mongolian population moved from the north of China to the Yunnan region in the south of C...

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Detalles Bibliográficos
Autores principales: Sun, Hao, Yang, Zhaoqing, Lin, Keqin, Liu, Shuyuan, Huang, Kai, Wang, Xiuyun, Chu, Jiayou, Huang, Xiaoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521750/
https://www.ncbi.nlm.nih.gov/pubmed/26230582
http://dx.doi.org/10.1371/journal.pone.0134334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521750/
https://www.ncbi.nlm.nih.gov/pubmed/26230582
http://dx.doi.org/10.1371/journal.pone.0134334

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