Cargando…

Corp Regulates P53 in Drosophila melanogaster via a Negative Feedback Loop

The tumor suppressor P53 is a critical mediator of the apoptotic response to DNA double-strand breaks through the transcriptional activation of pro-apoptotic genes. This mechanism is evolutionarily conserved from mammals to lower invertebrates, including Drosophila melanogaster. P53 also transcripti...

Descripción completa

Detalles Bibliográficos
Autores principales: Chakraborty, Riddhita, Li, Ying, Zhou, Lei, Golic, Kent G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521751/
https://www.ncbi.nlm.nih.gov/pubmed/26230084
http://dx.doi.org/10.1371/journal.pgen.1005400