Cargando…
Corp Regulates P53 in Drosophila melanogaster via a Negative Feedback Loop
The tumor suppressor P53 is a critical mediator of the apoptotic response to DNA double-strand breaks through the transcriptional activation of pro-apoptotic genes. This mechanism is evolutionarily conserved from mammals to lower invertebrates, including Drosophila melanogaster. P53 also transcripti...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521751/ https://www.ncbi.nlm.nih.gov/pubmed/26230084 http://dx.doi.org/10.1371/journal.pgen.1005400 |