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Corp Regulates P53 in Drosophila melanogaster via a Negative Feedback Loop

The tumor suppressor P53 is a critical mediator of the apoptotic response to DNA double-strand breaks through the transcriptional activation of pro-apoptotic genes. This mechanism is evolutionarily conserved from mammals to lower invertebrates, including Drosophila melanogaster. P53 also transcripti...

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Detalles Bibliográficos
Autores principales:	Chakraborty, Riddhita, Li, Ying, Zhou, Lei, Golic, Kent G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521751/ https://www.ncbi.nlm.nih.gov/pubmed/26230084 http://dx.doi.org/10.1371/journal.pgen.1005400

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