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Inhibition of Prostaglandin Transporter (PGT) Promotes Perfusion and Vascularization and Accelerates Wound Healing in Non-Diabetic and Diabetic Rats

Peripheral ischemia, resulting from diminished arterial flow and defective local vascularization, is one of the main causes of impaired wound healing in diabetes. Vasodilatory prostaglandins (PGs), including PGE(2) and PGI(2), regulate blood flow in peripheral tissues. PGs also stimulate angiogenesi...

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Detalles Bibliográficos
Autores principales: Liu, Zhongbo, Benard, Outhiriaradjou, Syeda, Mahrukh M., Schuster, Victor L., Chi, Yuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521828/
https://www.ncbi.nlm.nih.gov/pubmed/26230411
http://dx.doi.org/10.1371/journal.pone.0133615