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Optimal Threshold Determination for Interpreting Semantic Similarity and Particularity: Application to the Comparison of Gene Sets and Metabolic Pathways Using GO and ChEBI

BACKGROUND: The analysis of gene annotations referencing back to Gene Ontology plays an important role in the interpretation of high-throughput experiments results. This analysis typically involves semantic similarity and particularity measures that quantify the importance of the Gene Ontology annot...

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Detalles Bibliográficos
Autores principales: Bettembourg, Charles, Diot, Christian, Dameron, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521860/
https://www.ncbi.nlm.nih.gov/pubmed/26230274
http://dx.doi.org/10.1371/journal.pone.0133579