Cargando…

Preferential Interactions and the Effect of Protein PEGylation

BACKGROUND: PEGylation is a strategy used by the pharmaceutical industry to prolong systemic circulation of protein drugs, whereas formulation excipients are used for stabilization of proteins during storage. Here we investigate the role of PEGylation in protein stabilization by formulation excipien...

Descripción completa

Detalles Bibliográficos
Autores principales: Holm, Louise Stenstrup, Thulstrup, Peter W., Kasimova, Marina R., van de Weert, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521882/
https://www.ncbi.nlm.nih.gov/pubmed/26230338
http://dx.doi.org/10.1371/journal.pone.0133584