Down Syndrome Cognitive Phenotypes Modeled in Mice Trisomic for All HSA 21 Homologues

Down syndrome (DS), trisomy for chromosome 21, is the most common genetic cause of intellectual disability. The genomic regions on human chromosome 21 (HSA21) are syntenically conserved with regions on mouse chromosomes 10, 16, and 17 (Mmu10, Mmu16, and Mmu17). Recently, we created a genetic model o...

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Detalles Bibliográficos
Autores principales: Belichenko, Pavel V., Kleschevnikov, Alexander M., Becker, Ann, Wagner, Grant E., Lysenko, Larisa V., Yu, Y. Eugene, Mobley, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521889/
https://www.ncbi.nlm.nih.gov/pubmed/26230397
http://dx.doi.org/10.1371/journal.pone.0134861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521889/
https://www.ncbi.nlm.nih.gov/pubmed/26230397
http://dx.doi.org/10.1371/journal.pone.0134861

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