A Single RNaseIII Domain Protein from Entamoeba histolytica Has dsRNA Cleavage Activity and Can Help Mediate RNAi Gene Silencing in a Heterologous System

Dicer enzymes process double-stranded RNA (dsRNA) into small RNAs that target gene silencing through the RNA interference (RNAi) pathway. Dicer enzymes are complex, multi-domain RNaseIII proteins, however structural minimalism of this protein has recently emerged in parasitic and fungal systems. The...

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Detalles Bibliográficos
Autores principales: Pompey, Justine M., Foda, Bardees, Singh, Upinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521922/
https://www.ncbi.nlm.nih.gov/pubmed/26230096
http://dx.doi.org/10.1371/journal.pone.0133740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521922/
https://www.ncbi.nlm.nih.gov/pubmed/26230096
http://dx.doi.org/10.1371/journal.pone.0133740

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