Protein structure determination by combining sparse NMR data with evolutionary couplings

Accurate protein structure determination by NMR is challenging for larger proteins, for which experimental data is often incomplete and ambiguous. Fortunately, the upsurge in evolutionary sequence information and advances in maximum entropy statistical methods now provide a rich complementary source...

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Detalles Bibliográficos
Autores principales: Tang, Yuefeng, Huang, Yuanpeng Janet, Hopf, Thomas A., Sander, Chris, Marks, Debora S., Montelione, Gaetano T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521990/
https://www.ncbi.nlm.nih.gov/pubmed/26121406
http://dx.doi.org/10.1038/nmeth.3455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521990/
https://www.ncbi.nlm.nih.gov/pubmed/26121406
http://dx.doi.org/10.1038/nmeth.3455

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