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Protein structure determination by combining sparse NMR data with evolutionary couplings
Accurate protein structure determination by NMR is challenging for larger proteins, for which experimental data is often incomplete and ambiguous. Fortunately, the upsurge in evolutionary sequence information and advances in maximum entropy statistical methods now provide a rich complementary source...
Autores principales: | Tang, Yuefeng, Huang, Yuanpeng Janet, Hopf, Thomas A., Sander, Chris, Marks, Debora S., Montelione, Gaetano T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521990/ https://www.ncbi.nlm.nih.gov/pubmed/26121406 http://dx.doi.org/10.1038/nmeth.3455 |
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