Chemical shift guided homology modeling of larger proteins

We describe an alternate approach to protein structure determination that relies on experimental NMR chemical shifts, plus sparse NOEs if available. The newly introduced alignment method, POMONA, directly exploits the powerful bioinformatics algorithms previously developed for sequence-based homolog...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Yang, Bax, Ad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521993/
https://www.ncbi.nlm.nih.gov/pubmed/26053889
http://dx.doi.org/10.1038/nmeth.3437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521993/
https://www.ncbi.nlm.nih.gov/pubmed/26053889
http://dx.doi.org/10.1038/nmeth.3437

Ejemplares similares