Molecular Basis for 5-Carboxycytosine Recognition by RNA Polymerase II Elongation Complex

DNA methylation at selective cytosine residues (5mC) and their removal by TET-mediated DNA demethylation are critical for setting up pluripotent states in early embryonic development(1–2). TET enzymes successively convert 5mC to 5hmC, 5fC, and 5caC, the latter two of which are subject to removal by...

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Detalles Bibliográficos
Autores principales: Wang, Lanfeng, Zhou, Yu, Xu, Liang, Xiao, Rui, Lu, Xingyu, Chen, Liang, Chong, Jenny, Li, Hairi, He, Chuan, Fu, Xiang-Dong, Wang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521995/
https://www.ncbi.nlm.nih.gov/pubmed/26123024
http://dx.doi.org/10.1038/nature14482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521995/
https://www.ncbi.nlm.nih.gov/pubmed/26123024
http://dx.doi.org/10.1038/nature14482

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