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Pleiotropic effect of the proton pump inhibitor esomeprazole leading to suppression of lung inflammation and fibrosis

BACKGROUND: The beneficial outcome associated with the use of proton pump inhibitors (PPIs) in idiopathic pulmonary fibrosis (IPF) has been reported in retrospective studies. To date, no prospective study has been conducted to confirm these outcomes. In addition, the potential mechanism by which PPI...

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Detalles Bibliográficos
Autores principales: Ghebremariam, Yohannes T, Cooke, John P, Gerhart, William, Griego, Carol, Brower, Jeremy B, Doyle-Eisele, Melanie, Moeller, Benjamin C, Zhou, Qingtao, Ho, Lawrence, de Andrade, Joao, Raghu, Ganesh, Peterson, Leif, Rivera, Andreana, Rosen, Glenn D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522053/
https://www.ncbi.nlm.nih.gov/pubmed/26231702
http://dx.doi.org/10.1186/s12967-015-0614-x