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Cytidine-5-diphosphocholine reduces microvascular permeability during experimental endotoxemia
BACKGROUND: Microvascular permeability and leukocyte adhesion are pivotal mechanisms in sepsis pathophysiology contributing to the development of shock and mortality. No effective pharmacological therapy is currently available to restore microvascular barrier function in sepsis. Cholinergic mediator...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522138/ https://www.ncbi.nlm.nih.gov/pubmed/26232247 http://dx.doi.org/10.1186/s12871-015-0086-9 |