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Cytidine-5-diphosphocholine reduces microvascular permeability during experimental endotoxemia

BACKGROUND: Microvascular permeability and leukocyte adhesion are pivotal mechanisms in sepsis pathophysiology contributing to the development of shock and mortality. No effective pharmacological therapy is currently available to restore microvascular barrier function in sepsis. Cholinergic mediator...

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Detalles Bibliográficos
Autores principales:	Schmidt, Karsten, Hernekamp, Jochen Frederick, Doerr, Miriam, Zivkovic, Aleksandar R., Brenner, Thorsten, Walther, Andreas, Weigand, Markus A., Hofer, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522138/ https://www.ncbi.nlm.nih.gov/pubmed/26232247 http://dx.doi.org/10.1186/s12871-015-0086-9

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