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Prediction of problematic complexes from PPI networks: sparse, embedded, and small complexes
BACKGROUND: The prediction of protein complexes from high-throughput protein-protein interaction (PPI) data remains an important challenge in bioinformatics. Three groups of complexes have been identified as problematic to discover. First, many complexes are sparsely connected in the PPI network, an...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522147/ https://www.ncbi.nlm.nih.gov/pubmed/26231465 http://dx.doi.org/10.1186/s13062-015-0067-4 |