Cargando…

Prediction of problematic complexes from PPI networks: sparse, embedded, and small complexes

BACKGROUND: The prediction of protein complexes from high-throughput protein-protein interaction (PPI) data remains an important challenge in bioinformatics. Three groups of complexes have been identified as problematic to discover. First, many complexes are sparsely connected in the PPI network, an...

Descripción completa

Detalles Bibliográficos
Autores principales: Yong, Chern Han, Wong, Limsoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522147/
https://www.ncbi.nlm.nih.gov/pubmed/26231465
http://dx.doi.org/10.1186/s13062-015-0067-4