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Myocyte contractility can be maintained by storing cells with the myosin ATPase inhibitor 2,3 butanedione monoxime

Isolated intact myocytes can be used to investigate contractile mechanisms and to screen new therapeutic compounds. These experiments typically require euthanizing an animal and isolating fresh cells each day or analyzing cultured myocytes, which quickly lose their rod-shaped morphology. Recent data...

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Detalles Bibliográficos
Autores principales: Chung, Charles S, Mechas, Charles, Campbell, Kenneth S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522161/
https://www.ncbi.nlm.nih.gov/pubmed/26116551
http://dx.doi.org/10.14814/phy2.12445