Optimization and Evaluation of 5-Styryl-Oxathiazol-2-one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents

This is the first report of 5-styryl-oxathiazol-2-ones as inhibitors of the Mycobacterium tuberculosis (Mtb) proteasome. As part of the study, the structure–activity relationship of oxathiazolones as Mtb proteasome inhibitors has been investigated. Furthermore, the prepared compounds displayed a goo...

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Detalles Bibliográficos
Autores principales: Russo, Francesco, Gising, Johan, Åkerbladh, Linda, Roos, Annette K, Naworyta, Agata, Mowbray, Sherry L, Sokolowski, Anders, Henderson, Ian, Alling, Torey, Bailey, Mai A, Files, Megan, Parish, Tanya, Karlén, Anders, Larhed, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522185/
https://www.ncbi.nlm.nih.gov/pubmed/26246997
http://dx.doi.org/10.1002/open.201500001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522185/
https://www.ncbi.nlm.nih.gov/pubmed/26246997
http://dx.doi.org/10.1002/open.201500001

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