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Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer

The myc oncogene is overexpressed in almost half of all breast and ovarian cancers, but attempts at therapeutic interventions against myc have proven to be challenging. Myc regulates multiple biological processes, including the cell cycle, and as such is associated with cell proliferation and tumor...

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Detalles Bibliográficos
Autores principales: Seviour, E G, Sehgal, V, Lu, Y, Luo, Z, Moss, T, Zhang, F, Hill, S M, Liu, W, Maiti, S N, Cooper, L, Azencot, R, Lopez-Berestein, G, Rodriguez-Aguayo, C, Roopaimoole, R, Pecot, C, Sood, A K, Mukherjee, S, Gray, J W, Mills, G B, Ram, P T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522411/
https://www.ncbi.nlm.nih.gov/pubmed/25639871
http://dx.doi.org/10.1038/onc.2014.469