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Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer
The myc oncogene is overexpressed in almost half of all breast and ovarian cancers, but attempts at therapeutic interventions against myc have proven to be challenging. Myc regulates multiple biological processes, including the cell cycle, and as such is associated with cell proliferation and tumor...
Autores principales: | Seviour, E G, Sehgal, V, Lu, Y, Luo, Z, Moss, T, Zhang, F, Hill, S M, Liu, W, Maiti, S N, Cooper, L, Azencot, R, Lopez-Berestein, G, Rodriguez-Aguayo, C, Roopaimoole, R, Pecot, C, Sood, A K, Mukherjee, S, Gray, J W, Mills, G B, Ram, P T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522411/ https://www.ncbi.nlm.nih.gov/pubmed/25639871 http://dx.doi.org/10.1038/onc.2014.469 |
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