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Mouse Models as Predictors of Human Responses: Evolutionary Medicine

Mice offer a number of advantages and are extensively used to model human diseases and drug responses. Selective breeding and genetic manipulation of mice have made many different genotypes and phenotypes available for research. However, in many cases, mouse models have failed to be predictive. Impo...

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Detalles Bibliográficos
Autores principales: Uhl, Elizabeth W., Warner, Natalie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522464/
https://www.ncbi.nlm.nih.gov/pubmed/26246962
http://dx.doi.org/10.1007/s40139-015-0086-y