Cargando…

Ubiquitin is a versatile scaffold protein for the generation of molecules with de novo binding and advantageous drug-like properties

In the search for effective therapeutic strategies, protein-based biologicals are under intense development. While monoclonal antibodies represent the majority of these drugs, other innovative approaches are exploring the use of scaffold proteins for the creation of binding molecules with tailor-mad...

Descripción completa

Detalles Bibliográficos
Autores principales: Job, Florian, Settele, Florian, Lorey, Susan, Rundfeldt, Chris, Baumann, Lars, Beck-Sickinger, Annette G., Haupts, Ulrich, Lilie, Hauke, Bosse-Doenecke, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522466/
https://www.ncbi.nlm.nih.gov/pubmed/26258013
http://dx.doi.org/10.1016/j.fob.2015.07.002