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Cellular processes associated with LRRK2 function and dysfunction

Mutations in the leucine‐rich repeat kinase 2 (LRRK2)‐encoding gene are the most common cause of monogenic Parkinson's disease. The identification of LRRK2 polymorphisms associated with increased risk for sporadic Parkinson's disease, as well as the observation that LRRK2‐Parkinson's...

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Detalles Bibliográficos
Autores principales: Wallings, Rebecca, Manzoni, Claudia, Bandopadhyay, Rina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522467/
https://www.ncbi.nlm.nih.gov/pubmed/25899482
http://dx.doi.org/10.1111/febs.13305