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A mini-review on Biginelli adducts with notable pharmacological properties

Since the disclosure of Biginelli reaction by the chemist Pietro Biginelli, functionalized 3,4-dihydropyrimidin-2(1H)-ones/thiones (DHPMs) have emerged as prototypes for the design of compounds with a broad variety of biological activities. This mini-review describes over 100 Biginelli adducts demon...

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Detalles Bibliográficos
Autores principales: de Fátima, Ângelo, Braga, Taniris C., Neto, Leonardo da S., Terra, Bruna S., Oliveira, Breno G.F., da Silva, Daniel L., Modolo, Luzia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522545/
https://www.ncbi.nlm.nih.gov/pubmed/26257934
http://dx.doi.org/10.1016/j.jare.2014.10.006