Isoniazid prevents Nrf2 translocation by inhibiting ERK1 phosphorylation and induces oxidative stress and apoptosis

Isoniazid is used either alone or in combination with other drugs for the treatment of tuberculosis. It is also used for the prevention of tuberculosis. Chronic treatment of Isoniazid may cause severe liver damage leading to acute liver failure. The mechanism through which Isoniazid causes liver dam...

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Detalles Bibliográficos
Autores principales: Verma, Ajeet Kumar, Yadav, Arti, Dewangan, Jayant, Singh, Sarvendra Vikram, Mishra, Manisha, Singh, Pradhyumna Kumar, Rath, Srikanta Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522592/
https://www.ncbi.nlm.nih.gov/pubmed/26202867
http://dx.doi.org/10.1016/j.redox.2015.06.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522592/
https://www.ncbi.nlm.nih.gov/pubmed/26202867
http://dx.doi.org/10.1016/j.redox.2015.06.020

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