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Protease recognition sites in Bet v 1a are cryptic, explaining its slow processing relevant to its allergenicity
Despite a high similarity with homologous protein families, only few proteins trigger an allergic immune response with characteristic T(H)2 polarization. This puzzling observation is illustrated by the major birch pollen allergen Bet v 1a and its hypoallergenic protein isoforms, e.g., Bet v 1d. Give...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522599/ https://www.ncbi.nlm.nih.gov/pubmed/26235974 http://dx.doi.org/10.1038/srep12707 |