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Tailored delivery of analgesic ziconotide across a blood brain barrier model using viral nanocontainers

The blood brain barrier (BBB) is often an insurmountable obstacle for a large number of candidate drugs, including peptides, antibiotics, and chemotherapeutic agents. Devising an adroit delivery method to cross the BBB is essential to unlocking widespread application of peptide therapeutics. Present...

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Detalles Bibliográficos
Autores principales: Anand, Prachi, O’Neil, Alison, Lin, Emily, Douglas, Trevor, Holford, Mandë
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522602/
https://www.ncbi.nlm.nih.gov/pubmed/26234920
http://dx.doi.org/10.1038/srep12497