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Association between cytosolic expression of BRCA1 and metastatic risk in breast cancer

BACKGROUND: Although BRCA1 has been extensively studied for its role as a tumour-suppressor protein, the role of BRCA1 subcellular localisation in oncogenesis and tumour progression has remained unclear. This study explores the impact of BRCA1 mislocalisation on clinical outcomes in breast cancer. M...

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Detalles Bibliográficos
Autores principales: Santivasi, W L, Wang, H, Wang, T, Yang, Q, Mo, X, Brogi, E, Haffty, B G, Chakravarthy, A B, Xia, Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522623/
https://www.ncbi.nlm.nih.gov/pubmed/26057449
http://dx.doi.org/10.1038/bjc.2015.208