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Overexpression of the RNA-binding proteins Lin28B and IGF2BP3 (IMP3) is associated with chemoresistance and poor disease outcome in ovarian cancer

BACKGROUND: RNA-binding proteins have an important role in messenger RNA (mRNA) regulation during tumour development and carcinogenesis. In the present study, we examined the insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs; hereafter refered to as IMPs) and Lin28 family expressions in ep...

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Detalles Bibliográficos
Autores principales: Hsu, K-F, Shen, M-R, Huang, Y-F, Cheng, Y-M, Lin, S-H, Chow, N-H, Cheng, S-W, Chou, C-Y, Ho, C-L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522643/
https://www.ncbi.nlm.nih.gov/pubmed/26158423
http://dx.doi.org/10.1038/bjc.2015.254