Cargando…

The de novo synthesis of ubiquitin: identification of deubiquitinases acting on ubiquitin precursors

Protein ubiquitination, a major post-translational modification in eukaryotes, requires an adequate pool of free ubiquitin. Cells maintain this pool by two pathways, both involving deubiquitinases (DUBs): recycling of ubiquitin from ubiquitin conjugates and processing of ubiquitin precursors synthes...

Descripción completa

Detalles Bibliográficos
Autores principales: Grou, Cláudia P., Pinto, Manuel P., Mendes, Andreia V., Domingues, Pedro, Azevedo, Jorge E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522658/
https://www.ncbi.nlm.nih.gov/pubmed/26235645
http://dx.doi.org/10.1038/srep12836