Akt2 knock-down reveals its contribution to human lung cancer cell proliferation, growth, motility, invasion and endothelial cell tube formation

The Akt/PKB serine/threonine protein kinase consists of three isoforms: Akt-1, −2 and −3. Their overexpression has been detected in human cancers, but their roles in cancer progression are unclear. We investigated the impact of specific silencing of Akt1 and Akt2 on human lung cancer cell proliferat...

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Detalles Bibliográficos
Autores principales: Attoub, Samir, Arafat, Kholoud, Kamel Hammadi, Nasseredine, Mester, Jan, Gaben, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522680/
https://www.ncbi.nlm.nih.gov/pubmed/26234648
http://dx.doi.org/10.1038/srep12759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522680/
https://www.ncbi.nlm.nih.gov/pubmed/26234648
http://dx.doi.org/10.1038/srep12759

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