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Coarse-grained molecular dynamics studies of the translocation mechanism of polyarginines across asymmetric membrane under tension

Understanding interactions between cell-penetrating peptides and biomembrane under tension can help improve drug delivery and elucidate mechanisms underlying fundamental cellular events. As far as the effect of membrane tension on translocation, it is generally thought that tension should disorder t...

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Detalles Bibliográficos
Autores principales: He, XiaoCong, Lin, Min, Sha, BaoYong, Feng, ShangSheng, Shi, XingHua, Qu, ZhiGuo, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522684/
https://www.ncbi.nlm.nih.gov/pubmed/26235300
http://dx.doi.org/10.1038/srep12808