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Detection and Differentiation of Threonine- and Tyrosine-Monophosphorylated Forms of ERK1/2 by Capillary Isoelectric Focusing-Immunoassay

The extracellular signal regulated kinases ERK1/2 play important roles in the regulation of diverse cellular functions and have been implicated in several human diseases. In addition to the fully activated, diphosphorylated ERK1/2 protein, monophosphorylated forms of ERK1/2 have been observed, which...

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Detalles Bibliográficos
Autores principales: Kraus, Inga, Besong Agbo, Daniela, Otto, Markus, Wiltfang, Jens, Klafki, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522687/
https://www.ncbi.nlm.nih.gov/pubmed/26235103
http://dx.doi.org/10.1038/srep12767