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Simultaneous determination of four active components in rat plasma by ultra-high performance liquid chromatography tandem-mass spectrometry/mass spectrometry and its application to a pharmacokinetic study after oral administration of Callicarpa nudiflora extract

BACKGROUND: Callicarpa nudiflora has been commonly used as a Chinese folk medicine for resolving toxin, dispersing edema and hemostasis; however, its pharmacokinetic (PK) behavior remains unknown. In our present study, a simple and sensitive ultra-high performance liquid chromatography tandem mass s...

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Detalles Bibliográficos
Autores principales: Shao, Jun, Ma, Shuangcheng, Zheng, Dongkun, Chen, Weikang, Luo, Yuehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522836/
https://www.ncbi.nlm.nih.gov/pubmed/26246725
http://dx.doi.org/10.4103/0973-1296.160458