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Region-selective biosynthesis of artemisinic acid glycosides by crown galls of Panax quinquefolium and their in vitro antitumor activities

BACKGROUND: The biosynthesis of artemisinin derivatives is one of the interesting subjects. Artemisinic acid (AA) has been widely studied as a supposed intermediate in the biosynthetic pathway leading to artemisinin in Artemisia annua. OBJECTIVE: To investigate the bioconversion of AA by transgenic...

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Detalles Bibliográficos
Autores principales: Zhu, Jianhua, Chen, Lijia, Hu, Xianjing, Song, Liyan, Wang, Mingxuan, Yu, Rongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522837/
https://www.ncbi.nlm.nih.gov/pubmed/26246726
http://dx.doi.org/10.4103/0973-1296.160460