Regulatory T-Cell Development in the Human Thymus

The thymus generates a lineage-committed subset of regulatory T-cells (Tregs), best identified by the expression of the transcription factor FOXP3. The development of thymus-derived Tregs is known to require high-avidity interaction with MHC-self peptides leading to the generation of self-reactive T...

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Detalles Bibliográficos
Autores principales: Caramalho, Íris, Nunes-Cabaço, Helena, Foxall, Russell B., Sousa, Ana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522873/
https://www.ncbi.nlm.nih.gov/pubmed/26284077
http://dx.doi.org/10.3389/fimmu.2015.00395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522873/
https://www.ncbi.nlm.nih.gov/pubmed/26284077
http://dx.doi.org/10.3389/fimmu.2015.00395

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