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Microarray analysis of the in vivo response of microglia to Aβ peptides in mice with conditional deletion of the prostaglandin EP2 receptor

Amyloid-β (Aβ) peptides accumulate in the brains of patients with Alzheimer's disease (AD), where they generate a persistent inflammatory response from microglia, the innate immune cells of the brain. The immune modulatory cyclooxygenase/prostaglandin E2 (COX/PGE(2)) pathway has been implicated...

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Detalles Bibliográficos
Autores principales: Johansson, Jenny U., Woodling, Nathaniel S., Brown, Holden D., Wang, Qian, Andreasson, Katrin I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522932/
https://www.ncbi.nlm.nih.gov/pubmed/26251825
http://dx.doi.org/10.1016/j.gdata.2015.06.011