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Microarray analysis of the in vivo response of microglia to Aβ peptides in mice with conditional deletion of the prostaglandin EP2 receptor
Amyloid-β (Aβ) peptides accumulate in the brains of patients with Alzheimer's disease (AD), where they generate a persistent inflammatory response from microglia, the innate immune cells of the brain. The immune modulatory cyclooxygenase/prostaglandin E2 (COX/PGE(2)) pathway has been implicated...
Autores principales: | Johansson, Jenny U., Woodling, Nathaniel S., Brown, Holden D., Wang, Qian, Andreasson, Katrin I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522932/ https://www.ncbi.nlm.nih.gov/pubmed/26251825 http://dx.doi.org/10.1016/j.gdata.2015.06.011 |
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