Unsaturated fatty acids as high-affinity ligands of the C-terminal Per-ARNT-Sim domain from the Hypoxia-inducible factor 3α

Hypoxia-inducible transcription factors (HIF) form heterodimeric complexes that mediate cell responses to hypoxia. The oxygen-dependent stability and activity of the HIF-α subunits is traditionally associated to post-translational modifications such as hydroxylation, acetylation, ubiquitination, and...

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Detalles Bibliográficos
Autores principales: Fala, Angela M., Oliveira, Juliana F., Adamoski, Douglas, Aricetti, Juliana A., Dias, Marilia M., Dias, Marcio V. B., Sforça, Maurício L., Lopes-de-Oliveira, Paulo S., Rocco, Silvana A., Caldana, Camila, Dias, Sandra M. G., Ambrosio, Andre L. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522956/
https://www.ncbi.nlm.nih.gov/pubmed/26237540
http://dx.doi.org/10.1038/srep12698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522956/
https://www.ncbi.nlm.nih.gov/pubmed/26237540
http://dx.doi.org/10.1038/srep12698

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