Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques

HIV-1 mucosal transmission begins with virus or virus-infected cells moving through mucus across mucosal epithelium to infect CD4(+) T cells. Although broadly neutralizing antibodies (bnAbs) are the type of HIV-1 antibodies that are most likely protective, they are not induced with current vaccine c...

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Detalles Bibliográficos
Autores principales: Santra, Sampa, Tomaras, Georgia D., Warrier, Ranjit, Nicely, Nathan I., Liao, Hua-Xin, Pollara, Justin, Liu, Pinghuang, Alam, S. Munir, Zhang, Ruijun, Cocklin, Sarah L., Shen, Xiaoying, Duffy, Ryan, Xia, Shi-Mao, Schutte, Robert J., Pemble IV, Charles W., Dennison, S. Moses, Li, Hui, Chao, Andrew, Vidnovic, Kora, Evans, Abbey, Klein, Katja, Kumar, Amit, Robinson, James, Landucci, Gary, Forthal, Donald N., Montefiori, David C., Kaewkungwal, Jaranit, Nitayaphan, Sorachai, Pitisuttithum, Punnee, Rerks-Ngarm, Supachai, Robb, Merlin L., Michael, Nelson L., Kim, Jerome H., Soderberg, Kelly A., Giorgi, Elena E., Blair, Lily, Korber, Bette T., Moog, Christiane, Shattock, Robin J., Letvin, Norman L., Schmitz, Joern E., Moody, M. A., Gao, Feng, Ferrari, Guido, Shaw, George M., Haynes, Barton F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523205/
https://www.ncbi.nlm.nih.gov/pubmed/26237403
http://dx.doi.org/10.1371/journal.ppat.1005042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523205/
https://www.ncbi.nlm.nih.gov/pubmed/26237403
http://dx.doi.org/10.1371/journal.ppat.1005042

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