Potent anti-inflammatory effects of the narrow spectrum kinase inhibitor RV1088 on rheumatoid arthritis synovial membrane cells

BACKGROUND AND PURPOSE: To investigate whether a narrow spectrum kinase inhibitor RV1088, which simultaneously targets specific MAPKs, Src and spleen tyrosine kinase (Syk), is more effective at inhibiting inflammatory signalling in rheumatoid arthritis (RA) than single kinase inhibitors (SKIs). EXPE...

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Detalles Bibliográficos
Autores principales: To, Wing S, Aungier, Susan R, Cartwright, Alison J, Ito, Kazuhiro, Midwood, Kim S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523337/
https://www.ncbi.nlm.nih.gov/pubmed/25891413
http://dx.doi.org/10.1111/bph.13170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523337/
https://www.ncbi.nlm.nih.gov/pubmed/25891413
http://dx.doi.org/10.1111/bph.13170

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