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Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament severing proteins

Auditory sensory hair cells depend on stereocilia with precisely regulated lengths to detect sound. Since stereocilia are primarily composed of cross-linked, parallel actin filaments, regulated actin dynamics are essential for controlling stereocilia length. Here, we assessed stereocilia actin turno...

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Detalles Bibliográficos
Autores principales: Narayanan, Praveena, Chatterton, Paul, Ikeda, Akihiro, Ikeda, Sakae, Corey, David P., Ervasti, James M., Perrin, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523390/
https://www.ncbi.nlm.nih.gov/pubmed/25897778
http://dx.doi.org/10.1038/ncomms7855